Skip to main content

Navigation Navigation

Web Content Display Web Content Display

Seminar „Between physics, biology and medicine”

The seminar „Between physics, biology and medicine” is dedicated to the presentation of the latest achievements and research in the field of biophysics and medical physics. The hosts of the seminar are prof. Ewa Ł. Stępień, the head of the Department of Medical Physics, and prof. Paweł Moskal, the head of the Department of Experimental Particle Physics and Applications. The seminar is organized regularly every other Wednesday at 16:15 in lecture hall A-1-08.

The speakers of the seminar are invited guests from polish and foreign universities, our collaborators, scientists interested in application of physics in medical and biological research.

Past seminars

Web Content Display Web Content Display

Assoc. Prof. Barbara Błasiak (Institute of Nuclear Physics PAN, Cracow, Poland)

event-date: 04.02.2020

"Molecular Magnetic Resonance Imaging of Cancer using Core/Shell Nanoparticles"

February 4 2020 at 4:15 pm in aula A 1-08.​ Speaker: Assoc. Prof. Barbara Błasiak (Institute of Nuclear Physics Polish Academy of Sciences).

Curriculum vitae of the speaker

Announcement about the seminar


Magnetic Resonance Imaging (MRI) has been used for early cancer detection, treatment monitoring and image guided surgery. MRI has excellent spatial resolution and soft tissue contrast but low specificity. Standard contrast enhanced MRI based on tumors vasculature, including Gd-based T1 contrast agents, does not provide sufficiently high specificity for tumor diagnosis and thus contrast agents providing T2 contrast have been applied to provide information on tumor specificity. To improve the tumor contrast we have developed core/shell NaDyF4/NaGdF4 nanoparticles changing both T1 and T2 relaxation times of surrounding water molecules and conjugated them with tumor specific antibodies. The relaxation times (T1 and T2) of the nanoparticles with various score/shell sizes and concentrations were measured at 9.4T and 3T to find the optimum T1/T2 ratio for MRI. T1- and T2-weighted images using core/shell nanoparticles of the animal models of brain, breast and prostate cancer were collected and combined to provide enhanced contrast and edges.


Published Date: 20.01.2020
Published by: Tomasz Malarz