4th Jagiellonian Symposium on Advances in Particle Physics and Medicine was organised by the Jagiellonian University in Kraków, Poland. The conference took place July 10 – 15, 2022 in Collegium Maius, the oldest building of the University founded in XIV century as well as in the Collegium Novodvorscianum. One of the main purposes of the Jagiellonian Symposium is to exchange experience and expertise gained by various institutions in the fields of nuclear and particle physics, medical imaging, radiotherapy and diagnostics. One of the keynote speakers at the Symposium was Prof. Abass Alavi who was the first to administer 18F-FDG to a human subject, producing tomographic images of the brain. The conferences was also honored by an public lecture by Prof. Catalina Curceanu from National Laboratory of Frascati entitled “All in a thimble! Strangeness in the neutron stars?” During the conference, representatives of the Department of Medical Physics, Dr. Ewelina Kubicz-Staszkiewicz and Carina Rząca, MA, presented their results. On the other hand, the poster session was attended by Dr. Magdalena Marzec, Dominik Panek, MA, Monika Szczepanek, MA, and mgr Konrad Skórkiewicz, MA. The winners of the poster session were Monika Szczepanek presenting a poster titled "Determination of ¹⁰B concentration in melanocytes and melanoma cells" and Deepak Kumar with a poster entitled "Measurement of correlation between polarization of annihilation photons emitted in e+e- system to detect entanglement at subMeV range.”